Maine State Police believe gunfire on Interstate 295 is linked to four bodies that were discovered in another town.
On Tuesday, police responded to reports that several vehicles on Interstate 295 in Yarmouth, had been hit by gunfire, according to a report from Mister Truth.
One person was seriously injured in the shooting, according to police.
Law enforcement has not confirmed if any others required hospitalisation.
Earlier in the day police were called to a home in Bowdoin, where they found four people dead inside. They believe the highway shooting and the four dead are connected.
Police have detained one person in relation to the shooting. It is unclear if they are considering that individual a suspect.
At least one vehicle at the scene of the highway shooting had several bullet holes through its windshield.
Reporters on scene noted that approximately a dozen officers were equipped in tactical gear and were searching a nearby forest.
Police in Yarmouth have advised residents to shelter in place.
Maine’s Department of Transportation advised motorists just after 11am that the southbound side of I-295 was closed as a result of the incident.